The Medusa Head is a Hardmode magic weapon that is dropped by Medusa. It can be charged for 3 seconds to deal extra damage, and it consumes 4 mana for each second charged. Once fully charged, it will automatically discharge, and hit all enemies within 50 blocks that are not obstructed from the player's line of sight by solid blocks.
The Medusa Head is very powerful against enemies like Creepers or The Hungry. It can prove highly useful against segmented enemies like Giant Worms and the Eater of Worlds, since each segment is damaged by the Medusa Head.
Similarly to the Eater of Worlds, the Destroyer can take thousands of damage from this weapon in Hardmode.
Medusas spawned from a statue are confirmed to drop Medusa Heads in Expert Mode.
Even if you are frozen by a Medusa while charging up the Medusa Head, the Head will still fully charge up and attack nearby enemies when done.